tetrahydrofolate synthase
Enzyme information
Common names
tetrahydrofolate synthase
folylpolyglutamate synthase
folate polyglutamate synthetase
formyltetrahydropteroyldiglutamate synthetase
N10-formyltetrahydropteroyldiglutamate synthetase
folylpoly-gamma-glutamate synthase
folylpolyglutamyl synthetase
folylpoly(gamma-glutamate) synthase
folylpolyglutamate synthetase
folylpoly-gamma-glutamate synthetase-dihydrofolate synthetase
FPGS
tetrahydrofolylpolyglutamate synthase
tetrahydrofolate:L-glutamate gamma-ligase (ADP-forming)
tetrahydropteroyl-[gamma-Glu]n:L-glutamate gamma-ligase (ADP-forming)
6.3.2.17
EC Number
6.3.2.17
Links
Reactions
ATP + L-Glutamate + Tetrahydrofolate = ADP + Orthophosphate + Tetrahydrofolyl-[Glu](2)
ATP + L-Glutamate + 10-Formyltetrahydrofolate = ADP + Orthophosphate + 10-Formyltetrahydrofolyl L-glutamate
ATP + L-Glutamate + Dihydropteroate = ADP + Orthophosphate + Dihydrofolate