cholate---CoA ligase
Enzyme information
Common names
cholate---CoA ligase
BAL
bile acid CoA ligase
bile acid coenzyme A ligase
choloyl-CoA synthetase
choloyl coenzyme A synthetase
cholic thiokinase
cholate thiokinase
cholic acid:CoA ligase
3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl coenzyme A synthetase
3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate-CoA ligase
3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate-CoA synthetase
THCA-CoA ligase
3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanate---CoA ligase
3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanate:CoA ligase (AMP-forming)
cholyl-CoA synthetase
trihydroxycoprostanoyl-CoA synthetase
6.2.1.7
EC Number
6.2.1.7
Links
Reactions
ATP + CoA + Cholic acid = Diphosphate + AMP + Choloyl-CoA
ATP + CoA + 3alpha,7alpha-Dihydroxy-5beta-cholestanate = Diphosphate + AMP + 3alpha,7alpha-Dihydroxy-5beta-cholestanoyl-CoA
ATP + CoA + 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanoate = Diphosphate + AMP + 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanoyl-CoA
ATP + CoA + 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanoate = Diphosphate + AMP + (25R)-3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-oyl-CoA
ATP + CoA + 3alpha,7alpha-Dihydroxy-5beta-cholestanate = Diphosphate + AMP + (25R)-3alpha,7alpha-Dihydroxy-5beta-cholestanoyl-CoA
Diphosphate + AMP + Chenodeoxycholoyl-CoA = ATP + CoA + Chenodeoxycholate