GTP cyclohydrolase I
Enzyme information
Common names
GTP cyclohydrolase I
GTP cyclohydrolase
guanosine triphosphate cyclohydrolase
guanosine triphosphate 8-deformylase
dihydroneopterin triphosphate synthase
GTP 8-formylhydrolase
3.5.4.16
EC Number
3.5.4.16
Links
Reactions
H2O + GTP = Formate + 2-Amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)dihydropteridine triphosphate
H2O + GTP = Formamidopyrimidine nucleoside triphosphate
H2O + 2-Amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)dihydropteridine triphosphate = 2,5-Diamino-6-(5'-triphosphoryl-3',4'-trihydroxy-2'-oxopentyl)-amino-4-oxopyrimidine
H2O + Formamidopyrimidine nucleoside triphosphate = Formate + 2,5-Diaminopyrimidine nucleoside triphosphate
2,5-Diaminopyrimidine nucleoside triphosphate = 2,5-Diamino-6-(5'-triphosphoryl-3',4'-trihydroxy-2'-oxopentyl)-amino-4-oxopyrimidine