hypoxanthine phosphoribosyltransferase
Enzyme information
Common names
hypoxanthine phosphoribosyltransferase
IMP pyrophosphorylase
transphosphoribosidase
hypoxanthine---guanine phosphoribosyltransferase
guanine phosphoribosyltransferase
GPRT
HPRT
guanosine 5'-phosphate pyrophosphorylase
IMP-GMP pyrophosphorylase
HGPRTase
6-hydroxypurine phosphoribosyltransferase
6-mercaptopurine phosphoribosyltransferase
GMP pyrophosphorylase
guanine-hypoxanthine phosphoribosyltransferase
guanosine phosphoribosyltransferase
guanylate pyrophosphorylase
guanylic pyrophosphorylase
inosinate pyrophosphorylase
inosine 5'-phosphate pyrophosphorylase
inosinic acid pyrophosphorylase
inosinic pyrophosphorylase
purine-6-thiol phosphoribosyltransferase
2.4.2.8
EC Number
2.4.2.8
Links
Reactions
Diphosphate + AMP = 5-Phospho-alpha-D-ribose 1-diphosphate + Adenine
Diphosphate + IMP = 5-Phospho-alpha-D-ribose 1-diphosphate + Hypoxanthine
Diphosphate + GMP = 5-Phospho-alpha-D-ribose 1-diphosphate + Guanine
Diphosphate + Xanthosine 5'-phosphate = 5-Phospho-alpha-D-ribose 1-diphosphate + Xanthine
5-Phospho-alpha-D-ribose 1-diphosphate + 6-Mercaptopurine = Diphosphate + 6-Thioinosine-5'-monophosphate
5-Phospho-alpha-D-ribose 1-diphosphate + 6-Methylmercaptopurine = Diphosphate + 6-Methylthiopurine 5'-monophosphate ribonucleotide
5-Phospho-alpha-D-ribose 1-diphosphate + Thioguanine = Diphosphate + 6-Thioguanosine monophosphate