thiopurine S-methyltransferase
Enzyme information
Common names
thiopurine S-methyltransferase
mercaptopurine methyltransferase
thiopurine methyltransferase
6-thiopurine transmethylase
TPMT
2.1.1.67
EC Number
2.1.1.67
Links
Reactions
S-Adenosyl-L-methionine + Thiopurine = S-Adenosyl-L-homocysteine + 6-Methylmercaptopurine
S-Adenosyl-L-methionine + 6-Mercaptopurine = S-Adenosyl-L-homocysteine + 6-Methylmercaptopurine
S-Adenosyl-L-methionine + 6-Thioinosine-5'-monophosphate = S-Adenosyl-L-homocysteine + 6-Methylthiopurine 5'-monophosphate ribonucleotide
S-Adenosyl-L-methionine + 6-Thioguanosine monophosphate = S-Adenosyl-L-homocysteine + 6-Methylthioguanosine monophosphate