leucine dehydrogenase
Enzyme information
Common names
leucine dehydrogenase
L-leucine dehydrogenase
L-leucine:NAD+ oxidoreductase, deaminating
LeuDH
1.4.1.9
EC Number
1.4.1.9
Links
Reactions
H2O + NAD+ + alpha-Amino acid = NADH + NH3 + H+ + 2-Oxo acid
H2O + NADP+ + alpha-Amino acid = NADPH + NH3 + H+ + 2-Oxo acid
H2O + NAD+ + L-Leucine = NADH + NH3 + H+ + 4-Methyl-2-oxopentanoate
H2O + NAD+ + L-Valine = NADH + NH3 + H+ + 3-Methyl-2-oxobutanoic acid
H2O + NAD+ + L-Isoleucine = NADH + NH3 + H+ + (S)-3-Methyl-2-oxopentanoic acid
H2O + NAD+ + (3R)-beta-Leucine = NADH + NH3 + H+ + beta-Ketoisocaproate