Delta4-3-oxosteroid 5beta-reductase
Enzyme information
Common names
Delta4-3-oxosteroid 5beta-reductase
3-oxo-Delta4-steroid 5beta-reductase
5beta-reductase
androstenedione 5beta-reductase
cholestenone 5beta-reductase
cortisone 5beta-reductase
cortisone beta-reductase
cortisone Delta4-5beta-reductase
steroid 5beta-reductase
testosterone 5beta-reductase
Delta4-3-ketosteroid 5beta-reductase
Delta4-5beta-reductase
Delta4-hydrogenase
4,5beta-dihydrocortisone:NADP+ Delta4-oxidoreductase
3-oxo-5beta-steroid:NADP+ Delta4-oxidoreductase
1.3.1.3
EC Number
1.3.1.3
Links
Reactions
NADP+ + 5beta-Androstane-3,17-dione = NADPH + H+ + Androstenedione
NADPH + H+ + Progesterone = NADP+ + 5beta-Pregnane-3,20-dione
NADP+ + 5beta-Dihydrotestosterone = NADPH + H+ + Testosterone
NADP+ + 5beta-Cholestan-3-one = NADPH + H+ + Cholest-4-en-3-one
NADP+ + 11beta,17alpha,21-Trihydroxy-5beta-pregnane-3,20-dione = NADPH + H+ + Cortisol
NADP+ + 17alpha,21-Dihydroxy-5beta-pregnane-3,11,20-trione = NADPH + H+ + Cortisone
NADP+ + 11beta,21-Dihydroxy-3,20-oxo-5beta-pregnan-18-al = NADPH + H+ + Aldosterone
NADP+ + 11beta,21-Dihydroxy-5beta-pregnane-3,20-dione = NADPH + H+ + Corticosterone
NADP+ + 7alpha-Hydroxy-5beta-cholestan-3-one = NADPH + H+ + 7alpha-Hydroxycholest-4-en-3-one
NADP+ + 7alpha,12alpha-Dihydroxy-5beta-cholestan-3-one = NADPH + H+ + 4-Cholesten-7alpha,12alpha-diol-3-one