dihydropyrimidine dehydrogenase (NADP+)
Enzyme information
Common names
dihydropyrimidine dehydrogenase (NADP+)
dihydrothymine dehydrogenase
dihydrouracil dehydrogenase (NADP+)
4,5-dihydrothymine: oxidoreductase
DPD
DHPDH
dehydrogenase, dihydrouracil (nicotinamide adenine dinucleotide phosphate)
DHU dehydrogenase
hydropyrimidine dehydrogenase
1.3.1.2
EC Number
1.3.1.2
Links
Reactions
NADP+ + 5,6-Dihydrouracil = NADPH + H+ + Uracil
NADP+ + 5,6-Dihydrothymine = NADPH + H+ + Thymine
NADPH + H+ + 5-FU = NADP+ + 5,6-Dihydro-5-fluorouracil