pyruvate dehydrogenase (acetyl-transferring)
Enzyme information
Common names
pyruvate dehydrogenase (acetyl-transferring)
MtPDC (mitochondrial pyruvate dehydogenase complex)
pyruvate decarboxylase
pyruvate dehydrogenase
pyruvate dehydrogenase (lipoamide)
pyruvate dehydrogenase complex
pyruvate:lipoamide 2-oxidoreductase (decarboxylating and acceptor-acetylating)
pyruvic acid dehydrogenase
pyruvic dehydrogenase
1.2.4.1
EC Number
1.2.4.1
Links
Reactions
Pyruvate + Thiamin diphosphate = CO2 + 2-(alpha-Hydroxyethyl)thiamine diphosphate
NAD+ + CoA + Pyruvate = NADH + CO2 + Acetyl-CoA + H+
Pyruvate + Enzyme N6-(lipoyl)lysine = CO2 + [Dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine
2-(alpha-Hydroxyethyl)thiamine diphosphate + Enzyme N6-(lipoyl)lysine = Thiamin diphosphate + [Dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine