ketosteroid monooxygenase
Enzyme information
Common names
ketosteroid monooxygenase
steroid-ketone monooxygenase
progesterone, NADPH2:oxygen oxidoreductase (20-hydroxylating, ester-producing)
17alpha-hydroxyprogesterone, NADPH2:oxygen oxidoreductase (20-hydroxylating, side-chain cleaving)
androstenedione, NADPH2:oxygen oxidoreductase (17-hydroxylating, lactonizing)
1.14.13.54
EC Number
1.14.13.54
Links
Reactions
NADPH + Oxygen + H+ + Progesterone = H2O + NADP+ + Testosterone acetate
NADPH + Oxygen + H+ + Ketosteroid = H2O + NADP+ + Steroid ester
NADPH + Oxygen + H+ + Ketosteroid = H2O + NADP+ + Steroid lactone
NADPH + Oxygen + H+ + Androstenedione = H2O + NADP+ + Testololactone
NADPH + Oxygen + H+ + 17alpha-Hydroxyprogesterone = H2O + NADP+ + Acetate + Androstenedione