cholestanetriol 26-monooxygenase
Enzyme information
Common names
cholestanetriol 26-monooxygenase
5beta-cholestane-3alpha,7alpha,12alpha-triol 26-hydroxylase
5beta-cholestane-3alpha,7alpha,12alpha-triol hydroxylase
cholestanetriol 26-hydroxylase
sterol 27-hydroxylase
sterol 26-hydroxylase
cholesterol 27-hydroxylase
CYP27A
CYP27A1
cytochrome P450 27A1'
1.14.13.15
EC Number
1.14.13.15
Links
Reactions
NADPH + Oxygen + 3alpha,7alpha-Dihydroxy-5beta-cholestane = H2O + NADP+ + 3alpha,7alpha,26-Trihydroxy-5beta-cholestane
NADPH + Oxygen + 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestane = H2O + NADP+ + 3alpha,7alpha,12alpha,26-Tetrahydroxy-5beta-cholestane
NADPH + Oxygen + H+ + Cholesterol = H2O + NADP+ + Cholest-5-ene-3beta,26-diol
2 NADPH + 2 Oxygen + 2 H+ + 7alpha,26-Dihydroxy-4-cholesten-3-one = 3 H2O + 2 NADP+ + 7alpha-Hydroxy-3-oxo-4-cholestenoate
2 NADPH + 2 Oxygen + 2 H+ + Cholest-5-ene-3beta,26-diol = 3 H2O + 2 NADP+ + 3beta-Hydroxy-5-cholestenoate
3alpha,7alpha,26-Trihydroxy-5beta-cholestane = 3alpha,7alpha-Dihydroxy-5beta-cholestan-26-al
3alpha,7alpha,12alpha,26-Tetrahydroxy-5beta-cholestane = 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-al
NADPH + Oxygen + H+ + 3alpha,7alpha-Dihydroxy-5beta-cholestan-26-al = H2O + NADP+ + 3alpha,7alpha-Dihydroxy-5beta-cholestanate
NADPH + Oxygen + H+ + 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-al = H2O + NADP+ + 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanoate