progesterone reductase
Enzyme information
Common names
progesterone reductase
3beta-hydroxy-Delta5-C27-steroid oxidoreductase
3beta-hydroxy-Delta5-steroid dehydrogenase
Delta5-3beta-hydroxysteroid dehydrogenase
3beta-hydroxy-5-ene steroid dehydrogenase
3beta-hydroxy steroid dehydrogenase/isomerase
3beta-hydroxy-Delta5-C27-steroid dehydrogenase/isomerase
3beta-hydroxy-5-ene-steroid oxidoreductase
steroid-Delta5-3beta-ol dehydrogenase
3beta-HSDH
5-ene-3-beta-hydroxysteroid dehydrogenase
3beta-hydroxy-5-ene-steroid dehydrogenase
1.1.1.145
EC Number
1.1.1.145
Links
Reactions
NAD+ + Dehydroepiandrosterone = NADH + H+ + Androstenedione
NAD+ + Pregnenolone = NADH + H+ + Progesterone
NADH + H+ + Testosterone = NAD+ + Androstenediol
NADH + H+ + Cortisol = NAD+ + 11beta,17alpha,21-Trihydroxypregnenolone
NAD+ + 3beta-Hydroxy-delta5-steroid = NADH + H+ + 3-Oxo-delta5-steroid
NAD+ + 17alpha-Hydroxypregnenolone = NADH + H+ + 17alpha-Hydroxyprogesterone
NAD+ + 21-Hydroxypregnenolone = NADH + H+ + 11-Deoxycorticosterone
NADH + H+ + 16alpha-Hydroxyandrost-4-ene-3,17-dione = NAD+ + 16alpha-Hydroxydehydroepiandrosterone
NADH + H+ + 11-Deoxycortisol = NAD+ + 17alpha,21-Dihydroxypregnenolone